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834 articles
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Marchiafava Bignami Syndrome: A Review
Abstract: Marchiafava-Bignami syndrome (MBS) is a rare neurological disorder characterized by demyelination and necrosis of the corpus callosum, which is the main bundle of nerve fibers connecting the two hemispheres of the brain. MBS primarily affects individuals with chronic alcoholism, although cases unrelated to alcohol consumption have also been reported. The corpus callosum is affected in almost a pathognomonic way. The clinical presentation is based on neurological impairment, motor abnormalities, seizures, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 1, 2024 · pp. 21–25 Read article
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Unveiling Insights and Strategies for Cognitive Mental Acuity
Abstract: This comprehensive review focuses on the intricate facets of cognition, emphasizing its multifaceted nature rooted in thought, experience and sensory perception. The role of key brain regions, such as the prefrontal cortex, temporal lobes, parietal cortex, occipital cortex and cerebellum, is elucidated in shaping various mental functions. The pathophysiology of cognitive decline is examined, linking specific impairments to damage in distinct brain regions. The study delves into pharmacological and non-pharmacological …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 1, 2024 · pp. 1–10 Read article
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Underdiagnosis of Underlying Migraine in Benign Paroxysmal Positional Vertigo
Abstract: Migraine and vestibular migraine are the primary cause of headache in general population world widely. The prevalence shows that 1 in 10 people have migraine. Majorities of headache causes are undiagnosed properly and usually treated for symptomatic treatment without following correct guidelines. Standard treatment options for migraine include acute relief, lifestyle strategies, alternative remedies, and prophylactic drug. Most patients are managed in primary care using painkiller in many cases without …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 1, 2024 · pp. 11–15 Read article
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Late Onset Ataxia: A Case Report
Abstract: 57-year-old man with no prior history of any illness presented with subacute onset of gradually progressive gait ataxia, upper limb incoordination and speech issues. There was history suggestive of orthostatic hypotension and erectile dysfunction. On examination, there was normal cognition with gaze evoked nystagmus, scanning speech and limb incoordination in the form of past pointing, dysdiadochokinesia, and tandem walking abnormality suggestive of pan cerebellar involvement. The patient was evaluated with …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 1, 2024 · pp. 16–20 Read article
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Protective Effects of Phellinus linteus Polysaccharides Against Radiation-Induced Hematopoietic Damage in Bone Marrow of Mice
Abstract: Chemotherapy and radiation therapy, which are standard methods of treatment for various cancers, often result in suppression of hematopoiesis accompanied by reduction in the number of hematopoietic stem cells and their progeny. We investigated a clinically potential use of Phellinus linteus polysaccharide in the treatment of various cytopenias induced by radiotherapy. Mice were administered Phellinus linteus polysaccharide orally at a dosage of 100 mg/kg once daily for + consecutive days, …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 12–17 Read article
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Bypass Operation by Single-Style Esophageal Plasty Using Small Intestines for Patients with End-Stage Esophageal Cancer which was Impossible to be Cured Radically
Abstract: The purpose of the present study was to figure out the possibility of the bypass operation in esophageal cancer which is impossible to be cured radically and its effect on the survival rate and quality of life of the patients. In recent years, the incidence of esophageal cancer has been increasing thus there are many problems occurring in keeping the quality of life. Especially gastrostomy is done in order to …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 1–5 Read article
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Nutritional, Preventive, and Therapeutic Potential of Ma-ul-Shae’er (Barley Water) in the Unani System of Medicine: A Holistic Viewpoint
Abstract: In the Unani methodology of managing diseases, Ilaj-bil-Ghiza (dietotherapy) serves as a foundational principle. The initial course of treatment for any ailment entails prescribing specific diets or regulating the quality and quantity of food intake. In recent times, there has been a heightened public awareness regarding the health advantages of functional foods and nutraceuticals for disease prevention and overall well-being. Unani medicine provides a methodical classification of food, taking into …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 18–25 Read article
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Unraveling Ulcerogenesis: A Comprehensive Delve of Enteric & Nonenteric Ulcers
Abstract: Enteric ulcers present a multifaceted landscape encompassing both peptic and non-peptic varieties, demanding a thorough exploration of their manifestations, causes, and pathophysiology. At the forefront of understanding lie pivotal factors such as Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs usage, lifestyle choices, and stress, each wielding significant influence over ulcer development and progression. The intricate interplay of these factors underscores the complexity of enteric ulcer etiology. Helicobacter pylori infection—a prevalent culprit—inflicts …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 25–40 Read article
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Interplay of Thyroid Dynamics in Type 2 Diabetes: A Comprehensive Analytical Study at Government Medical College, Kota, and Affiliated Hospitals
Abstract: Diabetes mellitus is a prevalent endocrine metabolic condition that causes significant morbidity and mortality globally. Innumerable metabolic processes within our bodies depend on thyroid hormones. Excess or deficiency in insulin or thyroid hormones might cause functional problems. The intricate relationship between thyroid disorders and diabetes has been recognized for a considerable period. Patients with diabetes have been known to experience thyroid malfunction, the most prevalent kind of which is hypothyroidism. …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 6–11 Read article
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Review on Machine Learning Techniques for Heart Failure Analysis in Health Industries
Abstract: There are few bodily components as crucial as the heart. It aids in the filtration and distribution of blood to every area of a body. The world's biggest cause of death is heart disease. It has been reported that symptoms include breathing difficulties, fast heartbeat, and chest discomfort. They analyze this data on a regular basis. This review begins with a brief introduction of cardiac disease and the present methods …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 29–43 Read article
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Revolutionizing Drug Delivery: Recent Advances in Pharmaceutical Dosage Forms
Abstract: Recent advances in pharmaceutical dosage forms revolutionize drug delivery, prioritizing targeted therapy and patient well-being. Enhanced drug carriers address complex medical challenges, from high-grade gliomas to ocular drug delivery, maximizing therapeutic efficacy while minimizing adverse effects. Traditional dosage forms like tablets and capsules undergo meticulous formulation and manufacturing processes, integrating Quality by Design principles for consistent product quality. Liquid formulations encounter stability challenges, necessitating rigorous stability testing and pH monitoring. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 77–89 Read article
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A Surgical Exploration of the Mechanism and Regulation of the Respiratory System: A Conceptual Analysis
Abstract: The respiratory system plays a vital role in facilitating the movement of air in and out of the body, comprising a complex network of anatomical pathways. It is conventionally divided into two primary sections: the upper respiratory tract and the lower respiratory tract. Within the upper respiratory tract lie structures extending from the nasal passages down to the vocal cords, crucial for phonation. These vocal cords, composed of mucous membrane …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 1, 2024 · pp. 56–63 Read article
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Can Screw-only fixations of ACPHT acetabular fractures enhance stability as the standard buttress plate fixation provides?
Abstract: Background: Of acetabular fractures, anterior column posterior hemi-transverse(ACPHT) fractures commonly occur after a fall onto the hip in elderly population. When displaced in these fractures, open reduction and internal fixation using plate and screws is usually required to achieve good functional outcomes. The open procedures, however, involve high complication rates due to surgical invasion; therefore, percutaneous techniques by screw-only constructs have been advocated to minimize these complications. The purpose of …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 1, 2024 · pp. 64–73 Read article
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The Relationship Between HbA1c and Inflammatory Markers in Acute Ischemic Stroke with and without Diabetes Mellitus
Abstract: Background: Diabetes mellitus (DM) is a prominent risk factor for acute ischemic stroke (AIS), contributing significantly to morbidity and mortality worldwide. Although inflammatory markers like neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and C-reactive protein (CRP) are recognized as playing a role in the development of acute ischemic stroke (AIS), their association with diabetes mellitus (DM) in individuals affected by AIS remains uncertain. This study seeks to investigate the differences in …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 57–66 Read article
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Role of Therapeutic Index for Local Infections Score in Wound Assessment
Abstract: Local wound infections pose a significant challenge, often detected later, leading to complications like systemic infections. Global nomenclature lacks uniformity, resulting in varied treatments for similar diagnoses. Early intervention is crucial, advocating for local antimicrobial therapy with diverse active agents to avoid systemic antibiotics and mitigate bacterial resistance. The Therapeutic Index for Local Infections (TILI) score, innovated by the German society Initiative Chronis Che Wenden (ICW), emerges as a pivotal …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 44–48 Read article
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The Symbiosis Between Spherical Refractive Error Cylindrical Refractive Error
Abstract: This study aimed to acknowledge the link between spherical refractive error and cylindrical refractive error, which is crucial for diagnosing and managing visual abnormalities productively. This research employed a multi-center, cross-sectional, analytical, and retrospective approach to investigate refractive errors. The objective results were refined subjectively to the best visual acuity with conventional clinical representations of refraction using the sphere, cylinder, and axis. The gathered data underwent analysis utilizing statistical software …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 67–76 Read article
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The Curious Case of the Sphered Blood Cells: Unveiling Hereditary Spherocytosis
Abstract: Hereditary spherocytosis (HS) is an inherited blood disorder that disrupts the shape and flexibility of red blood cells (RBCs) due to genetic mutations. These abnormal, sphere-shaped RBCs, called spherocytes, are prematurely destroyed in the spleen, leading to hemolytic anemia. Symptoms range from mild fatigue to chronic weakness and shortness of breath. While incurable, Hereditary spherocytosis can be effectively managed. Regular monitoring, folic acid supplementation, and in severe cases, splenectomy (surgical …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 49–57 Read article
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An Insight into Childhood Malignancy
Abstract: Childhood cancers represent a significant public health concern, affecting a vulnerable population with unique biological and developmental characteristics. The aim of this article is to describe the main causes and different types of malignancies in childhood. By understanding the contributing factors towards malignancy in childhood one can plan for the preventive measures and early diagnosis and treatment modalities can be adopted. Even though the treatment patterns have improved, people are …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 07–12 Read article
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A study to assess the effect of nature-based sound therapy during weaning among Mechanically Ventilated patients admitted in intensive care units of a selected tertiary care hospital Ludhiana, Punjab
Abstract: Weaning is a gradual transition from full invasive ventilatory support to spontaneous ventilation with minimal support. This conducted to assess the effect of nature-based sound therapy among Mechanically Ventilated Patients admitted in Intensive Care units. An experimental design (randomized controlled trial) was used to assess the effect of nature-based sound therapy during weaning among Mechanically Ventilated patients.30 patients were drawn from the target population by using convenience sampling technique and …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 1, 2024 · pp. 44–48 Read article
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Development of an Innovative Nanotransdermal Formulation Utilizing an Optimal Combination of Acyclovir and Omeprazole to Improve Antiviral Efficacy
Abstract: The study effectively created nanogel formulations of Acyclovir and Omeprazole using the solvent diffusion technique. Among the various formulations (F1–F9), F9 was identified as the most suitable for gel preparation based on its pH evaluation. Drug content analysis, performed using UV-spectroscopy, confirmed the homogeneity of the prepared nanogels, which appeared opaque, free of lumps, particles, or aggregates. The spreadability assessment of F9 demonstrated excellent spreadability, while viscosity values for all …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 19–35 Read article