Antipyretic Effects of Whole Plant Extract of Nyctanthes arbortristis linn.

Mrunal Krishnarao Shirsat; Santosh Kumar Gupta

Abstract

Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} The antipyretic activity of Nyctanthes arbortristis linn extract is investigated for potential on normal body temperature and yeast-induced pyrexia in albino rats. The whole plant of Nyctanthes arbortristis linn at the doses of 200 mg/kg body weight p .o. showed significant reduction in normal body temperature and yeast-provoked elevated temperature in a dose-dependent manner. The effect also extended up to 4 hours after the drug administration. The anti-pyretic effect of whole plant extract was comparable to that of Paracetamol (150 mg/kg p.o.), a standard anti-pyretic agent.

Abstract

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