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Research and Reviews: A Journal of Pharmacology

Marburg Virus a Global Infectious Disease: A Review

  1. Sumel Ashique

Abstract

This single negative-stranded RNA virus was first found in 1967 in the German cities Marburg and Frankfurt and Belgrade. The reason behind this virus disease was infected grivet monkeys were imported from Uganda. This virus is often called Vervet monkey disease due to the initial association between non-human primates and viruses. This virus is the etiologic agent of Marburg hemorrhagic fever in humans and non-human primates. Replication mainly occurs through the human endothelial cell. In 2009 it was reported that Egyptian fruit bats (Rousettus aegyptiacus) were involved as a reservoir for the virus. Transmission mainly occurs through body fluids, unprotected sex, and broken and wounded skin. After incubation periods the symptoms such as chills, headache, myalgia, stomach pain appears. There is no such specific treatment for that virus except fluid therapy and proper oxygen supply. Modern diagnosis techniques including ELISA, PCR, etc.
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