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Research and Reviews: A Journal of Pharmacology

Laxative Activity of Root of Moringa pterygosperma

  1. Mahesh Krishnath Kambale
  2. M. Kumawat
  3. N. S. Naikwade
  4. D. D. Chougule

Abstract

Crude aqueous extract of root of Moringa pterygosperma (family: Moringaceae) at dose 100 and 200 mg/kg was investigated for laxative activity according to Cappaso et al. in albino rats that were compared with standard drug agar-agar (300 mg/kg, p.o.) in normal saline. The rats were fasted for 12 h before the experiment. After 8 h of drug administration, the faeces were collected and weighed. The extract was found to produce significant laxative activity in dose-dependant manner. The activity may be contributed to the phytoconstituents present.

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