STM Journals Peer-reviewed research from Consortium e-Learning Network

Research and Reviews : A Journal of Immunology

TREATMENT OF ALLERGIC RHINITIS

  1. PC Kathuria

Abstract

Allergic Rhinitis (AR) has high prevalence all over the world, significantly affecting the health & quality of life,school or work performance and significant financial impact. AR is considered to have complex association withgenetic and environmental factors in etiology. The interaction between AR and other airway diseases such asChronic Rhinosinusitis with or without nasal polyp or asthma, Local allergic rhinitis remains to be clarified. AR hasshown to be caused by high T2 cytokines, IL-4, IL-5 & IL-13 which induce impairment of the nasal epithelial barrierintegrity. In this review, we will summarize the risk factors, clinical, diagnostic criteria, potential molecularmechanism and therapeutic target by allergen immunotherapy (AIT) and biologicals.
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