Diverse microRNAs Expressed in Five Prominent Cancers Worldwide

Ariya SS; Baby Joseph

doi:10.37591/(rrjobi).v5i1.128

Abstract

MicroRNA being a small RNA molecule plays an important role in the process of transcription of gene to mRNA. The importance of several numbers of microRNAs has been studied till date. They are capable of aiding in normal functioning of an organism. At the same time, their expression can have serious effects in different diseases. Many numbers of miRNAs has been reported to play vital roles in progression as well as control of cancers. In some cases, the downregulation or upregulation of certain miRNA are reported to be the cause for diseases. But in some cases, certain miRNAs are reported to be capable of controlling the diseases either by exhibiting a high range of expression or expressing in low rate. This article concentrates on some of the miRNAs involved in breast, lung, colon, ovarian and hepatocellular carcinomas. Keywords: miRNA, non-coding RNA, carcinoma, breast cancer, colon cancer, hepatocellular carcinoma, lung cancer, ovarian cancer, PCR, microarray Cite this ArticleAriya S.S., Baby Joseph. Diverse microRNAs Expressed in Five Prominent Cancers Worldwide. Research & Reviews: A Journal of Bioinformatics. 2018; 5(1): 1–9p.