Research and Reviews: A Journal of Toxicology
Volume 5, Issue 2 (2015)
Published
Table of contents
-
Toxic Potential of Carbaryl on Reproductive and Fertility Parameter in Male Wister Albino Rats
Abstract: This study aims to evaluate the adverse effect of carbaryl on reproductive system of male Wister albino rats. Adult male Wister albino rats were orally administered with 50, 100 and 150 mg/kg body weight of carbaryl for 90 days. Animals from each group were sacrificed after the study period. Sperm count, sperm motility, antioxidant assay (SOD, CAT, LPO, and protein carbonyl), Hormones assay histological analysis and fertility parameters were performed …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 2, 2015 · pp. 1–6 Read article
-
Differential Response by Rotenone on Human Trabecular Meshwork and HeLa Cell Lines
Abstract: Cellular response towards a particular stress condition is dependent on a number of factors including genetic makeup, microenvironmental factors, nutrient availability etc. Cells under same stress condition respond differentially and may exhibit pro-apoptotic or anti-apoptotic behavior. Two quite different cell lines—the cancerous cells of HeLa and the Human Trabecular Meshwork (HTM) cell line with very different microenvironmental requirements behave very differently towards oxidative insult due to rotenone. Study of their …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 2, 2015 · pp. 14–22 Read article
-
Parameters of “Safety” in the Food Additive Industry: A Review of Risks and Benefits
Abstract: “Safety is in the eye of the beholder.” What is deemed “safe” by one observer may seem dangerous or risky to others. To approach this apparent quandary and assure ongoing scientific input, most food additives should be tested on laboratory animals and subsequently monitored if approved for human or animal consumption (i.e., parallel to the pathway for the approval of drugs). The term “safety” in the study of the toxicology …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 2, 2015 · pp. 7–13 Read article