Research and Reviews: A Journal of Toxicology
Volume 4, Issue 3 (2014)
Published
Table of contents
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Phytochemical Screening, Proximate Analysis and Acute Toxicity Study of Ethanolic Extract of Launaea taraxacifolia on Visceral Organs of Albino Rats
Abstract: Despite increase in the acceptance of herbs for the treatment of certain diseases, there are limited information on the effectiveness, safety and toxicity of herbs. In this study, proximate analysis, phytochemical screening and acute toxicity studies on the herbal recipe, Launaea taraxacifolia were carried out. Constituents of Launaea taraxacifolia were extracted using ethanol. Phytochemical screening and proximate analysis were carried out on the extract. Fifteen (15) albino rats, divided into …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 3, 2014 · pp. 1–8 Read article
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Brain GST Inhibition, An Additional Mode of Action Following Beta-Cyfluthrin Intoxication in Albino Rat
Abstract: The aim of the study was to reveal the neurotoxic effect of an orally administered beta-cyfluthrin, a type-II pyrethroid in albino rats on the basis of activity of brain GST (Glutathione-s-transferase), AChE (acetylcholinesterase) and of total proteins level at different doses 35.48 and 5.06, 2.53, 1.68, 1.27 mg/kg body weight, for acute (1 day) and sub-acute (7, 14, 21 and 28 days) treatments respectively. Results reveal that beta-cyfluthrin administration inhibits …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 3, 2014 · pp. 30–36 Read article
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The Effect of Vitamin C on the Reproductive Functions of Paraquat Intoxicated Male Albino Rats (Rattus norvegicus)
Abstract: Paraquat (PQ) is a bipyridylium herbicide applied around trees in Orchids and between crop rows to control broad-leaved and grassy weeds. Its oxidation results in the formation of superoxides and supernitrite species which causes damage to cellular components. Studies have implicated PQ as one of the pesticides that contributes to the reduction in male reproductive functions in humans and animals during exposure. This study, therefore, determined the antioxidant effect vitamin …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 3, 2014 · pp. 9–29 Read article