Research and Reviews: A Journal of Toxicology
Volume 3, Issue 2 (2013)
Published
Table of contents
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Effect of Ethylene Glycol Monomethyl Ether on Testicular Antioxidant System in Adult Rats
Abstract: Ethylene glycol monomethyl ether (EGME), an environmental contaminant, which is widely used as a solvent especially in lacquers, paints, dyes, pesticides, liquid soap, cleaning solution & cosmetic, chemical intermediates, as a diluent for hydraulic brake fluid etc on industrial scale, has been shown to induce reproductive abnormalities in male rats. The precise nature and mechanism of action of EGME on the male reproductive system is not clear. In the present …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 1–6 Read article
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Treatment of Korean Panax Ginseng against Cisplatin-Induced Toxicity in Rats Haematological and Histological Examination of Liver, Spleen and Kidney
Abstract: Vital goal of all anti-cancer therapies are to prevent the incidence of side effects either through more selective therapeutic methodology that target only neoplastic cells or through the use of complementary or alternative medicine. Present study investigated the effects of Panax ginseng (PG) on cisplatin-induced haematological and histopathological (liver, kidney and spleen) changes in rats. Rats were administered with PG (25, 50, 100 mg/kg) before or after an intraperitoneal injection …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 35–39 Read article
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Molecular Mechanism of Fluoride Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Fluorine (Fl) a member of the halogen family is the most electronegative and reactive of all the elements of the Periodic table. Chronic and acute exposures of fluoride leads to cardiovascular disease (hypertension and atherosclerosis), neurological disorders, gastrointestinal disturbances, liver disease, renal disease, reproductive effects, other health disorders and also affects the antioxidant system in the body. Furthermore, reactive oxygen species (ROS)-mediated oxidative damage is a common malady in fluoride …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 7–34 Read article