Research and Reviews: A Journal of Pharmaceutical Science
Volume 7, Issue 3 (2016)
Published
Table of contents
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Titrimetric and Spectrophotometric Assay of Diethylcarbamazine Citrate in Pharmaceuticals using Permanganate as Oxidant
Abstract: Two titrimetric and one spectrophotometric methods are described for the determination of diethylcarbamazine citrate in bulk drug and dosage forms using permanganate as an oxidimetric agent. In method A, the drug solution in H2SO4 is titrated directly at 800C to a pink end point. DEC was treated with a measured excess of standard permanganate in H2SO4 medium, and after a contact time of 5 min, the residual oxidant back titrated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 3, 2016 · pp. 1–11 Read article
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Colloidosomes: An Inherent Rigid Vesicle with Controlled Drug Distribution
Abstract: Colloidosomes are hollow capsules whose shell is composed of closely packed uniform colloidal particles. To date, colloidosomes have been fabricated using colloidal assembly at liquid-liquid interfaces. This system also solves the problem of insolubility, instability, rapid degradation and widely used in specialized areas like protein delivery, gene delivery, targeting to brain, tumour targeting, etc. In the series of vascular systems, colloidosome is the advanced tool in drug delivery. Colloidosomes have …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 3, 2016 · pp. 12–25 Read article
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Alcoholic and Aqueous Extract of Eucaluyptus Globules Posses Antimicrobial Activity and Antifungal Property Confined only to Alcoholic Extract
Abstract: Alcoholic and aqueous extract of leaves of Eucalyptus globulus was studied for in vitro for its antimicrobial and antifungal activity. The study was done against gram-positive bacteria (Staphylococcus aureus), gram-negative bacteria (Escherichia coil and Pseudomonas aeruginosa) and fungus (Candida albicans). The evaluation was done by determining its inhibition zone. Result demonstrated that alcoholic extract has broad spectrum antibacterial and antifungal activity on gram-positive bacteria, gram-negative bacteria and fungus, whereas the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 3, 2016 · pp. 26–29 Read article
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Factors Affecting Implementation of Pharmaceutical Care at Jimma University Specialized Hospital, South West Ethiopia
Abstract: Pharmaceutical care is the responsible provision of medicine therapy for the purpose of a definite outcome that improves a patient’s quality of life. It is a necessary element of healthcare and the concept implies the active participation of the patient in medicine therapy decisions and, the cooperation of healthcare providers across disciplines. This study was conducted to explore factors that affect the implementation of pharmaceutical care at Jimma University Specialized …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 3, 2016 · pp. 30–40 Read article
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High-Performance Liquid Chromatographic Assay of Nateglinide and its Stability Study
Abstract: Nateglinide (NTG) is a D-phenylalanine derivative used in the treatment of type-2 diabetes mellitus. An accurate, sensitive and reproducible high-performance liquid chromatographic (HPLC) method has been developed and validated for the quantification of NTG in pharmaceutical samples. The drug was eluted from Inertsil ODS 3V (150×4.6 mm; 5 µm particle size) column at 30á´¼C with a mobile phase consisting of phosphate buffer of pH 3.3 and methanol (70:30 v/v). The …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 3, 2016 · pp. 41–52 Read article