Research and Reviews: A Journal of Pharmaceutical Science
Volume 6, Issue 3 (2015)
Published
Table of contents
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Self-Medication Practice in Woliso Town, South West Shoa, Oromia Region, Ethiopia
Abstract: Self-medication is usually defined as intake of any type of drugs for treating oneself without professional supervision to relieve an illness. The objective of this study was to assess the practice of self-medication in Woliso town, South West Shoa, Oromia, Ethiopia. A community based cross-sectional study was conducted in Woliso town and the data was collected by semi-structured questionnaire, consisting questions on general demographic, socio-economic as well as on perceived …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 3, 2015 · pp. 1–12 Read article
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Herbal Coxibs: Nature’s Aspirin
Abstract: Pain is part and parcel of most health conditions from joint disorders to cancer. This explains why several researchers were hooked on to unraveling the deep puzzle behind the pain mechanism and finding a better way to relieving it with medicines that went far beyond killing pain alone. When a landmark outcome emerged and identified prostaglandins, the body’s chemical messengers, as the cause of inflammation, or pain, and that they …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 3, 2015 · pp. 13–22 Read article
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Cyclooxygenase 3 Inhibition: A Probable Mechanism of Acetaminophen in Human: A Review
Abstract: The key rate-limiting step in prostanoid and thromboxane biosynthesis is catalyzed by Cyclooxygenases (COXs) and is the target of nonsteroidal anti-inflammatory drugs (NSAIDs). Until recently, the existence of only two isoforms: COX-1 and COX-2; remained under debate as the anti-pyretic and analgesic property of acetaminophen (paracetamol) could not be explained by mere COX-1 or COX-2 blockades. A novel COX-1 splice variant termed COX-3, sensitive to acetaminophen, was recently discovered in …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 3, 2015 · pp. 23–29 Read article
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Abresham (Bombyx mori Cocoon): A House of a worm with Immense Medicinal Value
Abstract: Abresham is the cocoon shell produced by an insect Bombyx mori (silk worm). Silk worm is mainly depend on mulberry leaves and spun cocoon of silk filament around it. In Unani System of Medicine (USM), this cocoon is known as Abresham Kham and when cut into small pieces before roasting then it is termed as Abresham Kham Muqarraz. It is one of the most common animal origin drug used in …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 3, 2015 · pp. 30–41 Read article
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Pylorus Ligation Induced Gastric Ulcer Protection by Sesamum Indicum Ethanolic Seed Extract
Abstract: The present study was performed in pylorus ligation induced ulcer model in Wister rats, in which ability to provide gastric protection was studied at two different doses 200 and 400 mg/kg calculated based on the acute toxicity study. Gastric protection was evaluated by assessing various parameters like gastric volume, pH, total acidity, free acidity, ulcer index and percentage inhibition of ulceration. Ranitidine at 50 mg/kg was used as the standard …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 3, 2015 · pp. 42–49 Read article