Research and Reviews: A Journal of Pharmaceutical Science
Volume 12, Issue 2 (2025)
Published
Table of contents
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An Overview on Analytical Estimation of Citicoline
Abstract: Citicoline is a medication that is used to treat Alzheimer's disease. Citicoline is a nootropic (brainboosting) substance. It's utilized to treat brain insufficiency as well as other neurological conditions like stroke, trauma, and Parkinson's disease. The results of published analytical methods for the determination of Citicoline in biological and pharmaceutical formulations are summarized in this review article. Various techniques such as Spectrophotometry, liquid chromatography (LC), highperformance liquid chromatography (HPLC), ultra-performance …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 1–6 Read article
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A Research Study and Report on the Role of Clinical Pharmacy Services on the Management of Chronic Respiratory Disorder Asthma to an ESI Hospital
Abstract: Chronic respiratory disorder (CRDs) are disease of the airways and other structure of the lung. A number of the foremost common are asthma, chronic obstructive pulmonary disease (COPD), occupational lung diseases and pulmonary hypertension. Additionally, to tobacco smoke, other risk factors including air pollution, occupational chemicals and dusts, and frequent lower respiratory infections during childhood. CRDs aren’t curable, however kinds of treatment that help dilate major air passages and improve …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 13–24 Read article
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Liposome and Its Method of Preparation: A Review
Abstract: Liposomes are spherical vesicles that self-assemble and range in size from 20 nm to 10 m. They can be used as drug carriers for lipophilic, hydrophilic, and amphiphilic medications. Lipophilic and amphiphilic drugs can be encapsulated inside the lipophilic bilayer, whereas hydrophilic drugs can be integrated into the aqueous heart. Many liposomal preparations are currently undergoing clinical trials, with some of them being accepted for clinical use. By altering the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 25–30 Read article
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Virtual Screening of Novel 2-substituted -5-hydroxy-1- (2-methyl-3-morpholinopropyl)-1H-indole-3- carboxamide Derivatives for Estrogen Receptor alpha in AF-2 domain for effective Anticancer Treatment
Abstract: Present manuscript describes designing of novel 2-substituted -5-hydroxy-1-(2-methyl-3- morpholinopropyl)-1H-indole-3-carboxamide derivatives as specific ERα modulators, discuss the selection criteria for 1ERR, several interactions between the ligand and the amino acid residues that would probably elicit fruitful modulation of the receptor. Accordingly, a ligand was observed to yield Gscore of -10.016 which was found comparable with the standard ligand Raloxifene (-11.869). The present work has been designed to discover some novel 2-substituted …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 31–55 Read article
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Flash Chromtography and Its Analytical Application: A Review
Abstract: Different chromatography techniques such as TLC, HPTLC, HPLC etc. are mainly used for separation of mixture. The column chromatography was use in many laboratories for separation and purification of different components. The separation of components based on partitioning or adsorption of solute on stationary to purify the liquids and for reaction control in organic synthesis.Column chromatography is a time consuming process. Flash Chromatography is a development of novel preparative liquid …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 56–76 Read article
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Comparative Evaluation of Corneal Permeation of Indomethacin Using Different Vegetable Oil
Abstract: Topical administration of drugs is the most favoured route for management of ocular inflammation. About 90% of dose applied topically from such solutions is lost due to precorneal losses (nasolacrimal drainage) and tearing results in poor availability as contact time is less between drug and ocular tissue. An increased ocular contact time of the drug may be achieved by formulating the drug as an oil solution. In this study, invitro …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 7–12 Read article
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In vitro and in vivo Anti-Oxidant and Anti-Diabetic Evaluation of cladodes Crude Extract and Solvent fractions of Opuntia elatior mill (Cactaceae)
Abstract: Objective: Ariel part of Opuntia elatior (Cactaceae) has been used in folklare remedies to treat diabetes in America, Mexico and India. However, the anti-diabetic potential of cladodes of this medicinal plant is not scientifically validated and authenticated. The present study aimed to evaluate in vitro and in vivo anti-oxidant and anti-diabetic potential of methanol extracts and solvent fractions of O. elatior cladodes. Methods: Phytochemical analysis performed according to standard procedure. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 77–88 Read article