Research and Reviews: A Journal of Pharmacology
Volume 9, Issue 1 (2019)
Published
Table of contents
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A Review on the Evidence Base on the Management of Malaria
Abstract: Malaria has been one of the most important infectious diseases of humans for millennia. An estimated 3.3 billion people approximately one-half of the world’s population living in 109 countries—are at risk of contracting this serious and of ten life-threatening diseases. In India the National Malaria Eradication Programme (NMEP), started in 1956, achieved near complete disappearance of the disease in 1960s (from 75 million in 1950s to 0.1 million in 1960s). …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 1, 2019 · pp. 1–11 Read article
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Anxiety Due to Predator Odour as a Novel Tool for Evaluating Anxiolytic Drugs
Abstract: Development of anxiolytic drugs is impaired due to the absence of a proper and reliable method. We have used the ethological aspects of animals such as intent to mate and food avoidance to research an anxiolytic drug called Aforte. Our findings have clearly shown that the ethological parameters are more reliable than the conventional pharmacological test such as elevated plus maze test, rota rod test, forced swim test. The ethological …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 1, 2019 · pp. 12–15 Read article
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Phytochemical and Pharmacological Importance of Turmeric (Curcuma longa): A Review
Abstract: Curcuma longa L. is a member of the ginger family (Zingiberaceae) and used widely by the traditional medical practitioners for the treatment of various ailments. Due to high curcumin content Indian turmeric is very popular as compared to other countries. Rhizomes derived from Curcuma longa is commonly known as Haldi or Turmeric. Rhizomes are horizontal underground stems that send out shoot as well as roots. Turmeric constitutes of fat-soluble, polyphenolic …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 1, 2019 · pp. 16–23 Read article
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Combination of Withania somnifera and Centella asiatica for the Management of Anxiety and Stress: Promise for the Future
Abstract: Aim: the aim of the present study is to evaluate the anxiolytic effect of Aforte tablet formulated with the combination of Withania somnifera and Centella asiatica. Method: The anxiolytic effect of Aforte tablet was studied by ethogram and other conventional pharmacological studies such as Despair Swim test (DST), Elevated Plus Maze (EPZ) and Skeletal Muscle Relaxant Activity. Result: The study of ethogram of mice evaluated by focal animal sampling showed …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 1, 2019 · pp. 24–28 Read article
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Enhancement of Aqueous Solubility of Etoposide Using Solid Dispersion Technique
Abstract: Objective: The objective of present research work was to enhance the aqueous solubility of Etoposide using solid dispersion technique. Methods: Formulation of solid dispersion by using different polymers and their different ratio with the used of solid dispersion technique. Solid dispersion formulation F-1 to F-9 were prepared by using different type and different concentration of polymers like PEG-6000, PEG-4000 poloxomer 407 and ethanol respectively. Results: The solid dispersion formulation were …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 1, 2019 · pp. 29–37 Read article