Research and Reviews: A Journal of Pharmacology
Volume 5, Issue 2 (2015)
Published
Table of contents
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Participation of Nursing Professionals in Pharmacovigilance Programme of India
Abstract: Indian Pharmacopoeia Commission (IPC) functions as National Coordination Centre (NCC) for Pharmacovigilance Programme of India (PvPI) to monitor the adverse drug reactions (ADR). Healthcare professionals including nurses play a vital role in ADRs monitoring and reporting to NCC to ensure the safe use of medicines. NCC takes efforts to initiate nursing professionals to participate in PvPI to promote patients safety. To provide education and training to the nurses in ADRs …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 2, 2015 · pp. 1–4 Read article
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A Review on the Clinical and Pathological Significance of Prorenin Receptor [(P)RR]
Abstract: The (pro)renin receptor (P)RR discovery, which is a novel constituent of Renin Angiotensin-Aldosteron System (RAS) has brought renin and (pro)renin back into spotlight. The (P)RR binds both renin and its inactive precursor (pro)renin, this binding triggers a cascade of intracellular signalling that eventually leads to upregulation of the expression of profibrotic genes, potentially leading to pathogenesis of cardiac and renal fibrosis, growth and remodelling. Clinically, it is also seen that …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 2, 2015 · pp. 11–17 Read article
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Anti-Ulcer Activity of Ethanolic Extract of Sesamum indicum Seed on Indomethacin-Induced Ulcer Model and Its Antioxidant Property in Gastro-Protection
Abstract: The present study was intended to investigate and evaluate the antiulcer activity of the ethanol seed extract of Sesamum indicum Linn. using Indomethacin Induced Ulcer in Albino rats and to determine its link between oxidant or antioxidant parameter. The extract of Seamum indicum Linn. was tested on indomethacin induced gastric ulcer in Albino rats. The antiulcer activity of high dose (400 mg/kg) and low dose (200 mg/kg) of ethanolic extract …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 2, 2015 · pp. 18–25 Read article
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Assessment of Malaria Prevalence and Evaluation of Therapeutic Efficacy of Artemether/Lumefantrine (Coartem®) against Uncomplicated Falciparum Malaria in Wondogenet Woreda, SNNPR, Ethiopia
Abstract: Normal 0 false false false EN-US X-NONE X-NONE AbstractThe study was conducted to assess malaria prevalence and to evaluate therapeutic efficacy of Coartem® for the treatment of uncomplicated falciparum malaria in Wondogenet Woreda, Sidama Zone, Ethiopia. Since the spread of Plasmodium falciparum, parasite resistance to almost all antimalarial monotherapies is a serious impediment to malaria control. Artemether-lumefantrine (Coartem®) therapy has been in use as the first-line treatment for uncomplicated falciparum …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 2, 2015 · pp. 26–34 Read article
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Estimation of Excessive Addition of Fluoride in Dentifrices of Indian Market: The Present Status
Abstract: The addition of fluoride in dentifrices all over the world is done for the antibacterial and carries prevention. Drug Controller General of India (DCGI) has given a permissible limit for addition of fluoride in dentifrices 1000 ppm for adult and 500 ppm for children; as early as by G.O.I. Notification No. GSR 223(E) dated 19.4.1991. Besides, addition of the raw material also contain fluoride that leads further addition, which leads …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 2, 2015 · pp. 5–10 Read article