Research and Reviews: A Journal of Pharmacology
Volume 3, Issue 1 (2013)
Published
Table of contents
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A Possible Case of Methotrexate Induced Hepatic Cirrhosis
Abstract: A patient with psoriasis on long term methotrexate (MTX) therapy (cumulative dose=14.4 g) developed cirrhosis of liver associated with portal HTN and ascites. All the other possible causes for liver cirrhosis like HBV, HCV infection were ruled out. Investigations: antibodies (LKM-1), anti-mitochondrial antibodies (AMA 1,2,3,4,5,6,7,8,9), anti-treponemal antibody (TPHA), HBS Ag, anti-HCV were negative
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 1, 2013 Read article
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Anti-nociceptive Potential of Scurrula parasitica: An Unexploited Parasitic Plant
Abstract: Scurrula parasitica (Loranthaceae) is an herbaceous growing shrub parasitic on Dendrophthoe falcata (Loranthaceae) which is itself parasitic on Mangifera indica (Anacardiaceae). Scurrula parasitica is distributed throughout the western ghat region of Maharashtra, some parts of Uttar Karnataka and Tamil Nadu. Genus Scurrula comprising of around 91 species, however, only S. ferruginea, S. atropurpurea, S. fusca have been investigated systematically. No such pharmacological and phytochemical data are available on the plant …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 1, 2013 Read article
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Isolation, Characterization of Rhinacanthus Nasutus L. Kurz and Its Biological Evaluation
Abstract: The present paper deals with isolation, characterization and evaluation of anti-inflammatory, analgesic and anti-bacterial activities of n-hexane extract of Rhinacanthus nasutus L. Kurz. Extraction was carried out with soxhlet apparatus using solvents of increasing polarity. The anti-inflammatory activity was done by Carrageenan-Induced Paw Edema in rats. Analgesic activity was done by hot plate method and anti-bacterial activity by plate hole diffusion method. n-Hexane extract exhibited significant change in anti-inflammatory, analgesic …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 1, 2013 Read article