Research and Reviews: A Journal of Pharmacology
Volume 15, Issue 2 (2025)
Table of contents
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Erythrodermic Psoriasis: A Case Report Highlighting Clinical Features and Management
Abstract: Background: Erythrodermic psoriasis (EP) is a rare and severe variant of psoriasis that presents as widespread erythema, scaling, and systemic complications such as fever, dehydration, and electrolyte imbalances. It requires urgent medical attention due to the risk of life-threatening complications, including sepsis and multi-organ failure. The condition can arise de novo or as an exacerbation of pre-existing psoriasis, often triggered by medication withdrawal, infections, or systemic inflammation. Case Presentation: We …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 01–05 Read article
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The Reaction About Anti-Hypertensive Drugs According to Plasma Renin-Aldosterone States
Abstract: With recent studies, hypertension has not only a simple pathophysiology, thus it can classify details more about and establishing drug therapy strategies compatible with it is a very important method to improve the organ predictive of patients. The purpose of this study is to compare the responsibility of some anti-hypertensive drugs in hypertensive patients according to plasma renin-aldosterone levels, which becomes the background factor of hypertension. We investigated 71 hypertensive …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 14–23 Read article
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A Review of the Role of Fiber Supplements in Digestive Health and Weight Management
Abstract: The essential component of a nutritious diet is dietary fiber which enables body weight regulation and maintains digestive system health. Several supplements derived from fiber have gained popularity during recent years since they help improve gut health while controlling weight and preventing metabolic diseases. The two major groups which make up fiber are soluble and insoluble fibers that impact the body differently. The soluble fiber components psyllium inulin and beta-glucans …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 24–35 Read article
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Empowering Rural Healthcare in Tamil Nadu: A Framework for Patient-Centered Telemedicine
Abstract: Rural populations in Tamil Nadu often face challenges in accessing quality healthcare due to geographic isolation, limited resources, and shortages of healthcare professionals. Telemedicine has emerged as a transformative solution, offering a promising approach to bridge these gaps. This article presents a comprehensive framework for patient-centered telemedicine aimed at empowering rural healthcare in Tamil Nadu. By focusing on chronic disease management, particularly for conditions like hypertension and diabetes, this framework …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 36–42 Read article
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A Study on the Impact of Paracetamol on Male Reproductive System: A Mini Review
Abstract: Paracetamol, a widely used analgesic and antipyretic, has been studied for its potential effects on the male reproductive system. Paracetamol is a medication commonly used to relieve mild to moderate pain. Research suggests that prolonged or high-dose use of paracetamol may adversely affect male fertility by disrupting hormone regulation, impairing sperm production, and reducing testosterone levels. Studies have shown that paracetamol can interfere with the hypothalamic-pituitary-gonadal axis, leading to changes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 43–51 Read article
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Oral Health Among School Children in India: A Meta-Analysis
Abstract: Background: Good oral health is essential for overall well-being, and its foundation starts from a young age. Majority of people, especially school-aged children, suffer from dental conditions, such as gingivitis, periodontitis, and tooth decay. The Unani System of Medicine (USM) put a lot of emphasis on good oral health. According to the wisdom of USM, the entire health of an individual depends on their oral condition. Oral health is more …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 52–58 Read article
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Review on Unveiling the Shadow of Hyperpigmentation
Abstract: Natural products offer promising solutions for treating skin pigmentation disorders due to their non-toxic properties and effective mechanisms of action. Studies highlight their safety and efficacy through methods such as cytotoxicity tests, tyrosinase activity assays, and melanogenesis inhibition evaluations. Advanced delivery systems like liposomes and nanoparticles further enhance their performance by improving solubility and skin penetration. Skin pigmentation disorders, influenced by factors such as UV radiation, hormonal changes, and inflammation, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 59–66 Read article
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Future Prospects of AI in Pharmaceutical Industry and its Limitation
Abstract: The pharmaceutical industry is facing significant challenges, including prolonged drug development timelines, high costs, and low success rates in clinical trials. Traditional methods often result in inefficiencies, with new drug development taking over a decade and billions of dollars, yet most candidates fail in clinical trials due to issues like inefficacy or safety concerns. Artificial Intelligence (AI) has become a groundbreaking technology with the potential to tackle these issues effectively. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 6–13 Read article
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Neuro-Rehabilitation Reimagined: A Cross-Cultural Paradigm Integrating Immunotherapeutics and Multidimensional Analytics in Pediatric Cerebral Palsy
Abstract: Researchers performed multidimensional data analysis on the clinical records of 1,586 cerebral palsy pediatric patients to investigate the rehabilitative benefits of immunotherapy and the advantages of blending Traditional Chinese Medicine with Western treatments. A multi-center, prospective cohort study established a standardized system for data gathering that included clinical baseline databases along with treatment protocols and follow-up information. Baseline data analysis showed substantial patient diversity across clinical types and TCM syndromes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 67–84 Read article
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Pharmacogenomics in Anesthesia: Case Studies and Clinical Applications for Personalized Care
Abstract: Pharmacogenomics, the study of how genetic variability influences individual responses to medications, is transforming anesthetic practice by enabling personalized care. This case study collection explores the integration of pharmacogenomic insights into anesthesia management, highlighting its impact on safety, efficacy, and patient outcomes. Adverse reactions to anesthetics often arise from genetic polymorphisms that alter drug metabolism or sensitivity. For instance, patients with RYR1 mutations are susceptible to malignant hyperthermia (MH) when …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 85–91 Read article