Research and Reviews: Journal of Oncology and Hematology
Volume 7, Issue 2 (2018)
Published
Table of contents
-
Renin-Angiotensin System as a Therapeutic Target for Colorectal Cancer Liver Metastasis
Abstract: Classically, renin-angiotensin system (RAS), for a long time, has been perceived as the main regulator of cardiovascular homeostasis, due to its effect on blood vessels contraction or cardiac hypertrophy and is known to maintain blood pressure and body fluids. Hence, its pharmacological regulation is mainly associated with the management of hypertension. Currently, it was found that the RAS is involved in a broad range of physiological processes and diseases. RAS …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 2, 2018 · pp. 1–14 Read article
-
A Review of the Use of Direct Oral Anticoagulants for Treating Venous Thromboembolism in Patients with Cancer
Abstract: Venous thromboembolism is a common complication in patients with cancer. Treatment guidelines have long recommended low molecular weight heparin as the first-line therapy. There is a growing body of literature regarding direct oral anticoagulants in treating venous thromboembolism in these patients. The data regarding the use of direct oral anticoagulants in this population is reviewed as are the most current guidelines from the National Comprehensive Cancer Network. Keywords: Anticoagulants, venous …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 2, 2018 · pp. 15–17 Read article
-
Hairy Cell Leukemia: A Morphological Dilemma in Case of Low Peripheral Blood Hairy Cell Count
Abstract: Hairy cell leukemia (HCL) is a lympho-proliferative neoplasm of mature B cells with an indolent course, representing 2 to 3% of all leukemias. It clinically presents as bicytopenia and splenomegaly. We here present a case report where peripheral blood smear showed few lymphoid cells with hairy projections. A suspicion of hairy cell leukemia was given which was confirmed later on bone marrow aspiration and biopsy followed by flow cytometry which …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 2, 2018 · pp. 18–21 Read article
-
Brief Review on Novel Technology in Breast Cancer Chemotherapy
Abstract: Breast cancer is cancer that develops from breast tissue. Breast cells contain receptors for the two types of hormones estrogen and progesterone. They also contain receptors for a protein called HER2, which induce normal cell growth. Around two out of three women with breast cancer have cells that bear receptors for estrogen and progesterone, and just about 20–30% of breast cancers have too many HER2 receptors. Exploitation chemotherapy to treat …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 2, 2018 · pp. 22–26 Read article
-
A Short Review on CAR-T Cell Therapy in Cancer Treatment
Abstract: As an author in the present review, I have provided all the available information of CAR-T cell therapy like, definition, history of discovery, early FDA approval and types of clinical trials conducted, early manufacturers, current availability, preparation and mechanism involved, steps involved, adverse drug reactions, and its uses after referring to all available resources. I hope this review can be greatly helpful to all health care professionals, pharmacy, medical, nursing, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 2, 2018 · pp. 27–29 Read article