Research and Reviews: Journal of Oncology and Hematology
Volume 11, Issue 2 (2022)
Published
Table of contents
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Recurrent Pregnancy Loss and Thrombophilia: An insight
Abstract: By definition, thrombophilia refers to acquired and/or hereditary diseases that predispose people to venous and arterial thromboembolic events. The most common cause of death on the planet is thrombosis. Myocardial infarction and stroke are major causes of morbidity and mortality in the vascular system. The deep veins of the lower extremity are the most usually involved in venous thromboembolic events, which can lead to pulmonary emboli. Thromboembolism is the major …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 2, 2022 · pp. 1–7 Read article
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Immunology and Immunotherapy of Pulmonary adenocarcinoma: A Systematic Review
Abstract: Lung cancer is the world's second leading cause of death, with an estimated 9.6 million deaths in 2018. Approximately 80% of all lung cancer is caused by non-small cell lung cancer (NSCLC). Due to lack of early detection and treatment, the incidence rate of lung cancer prognosis remains low. CD4+T-lymphocytes, macrophages, dendritic cells, and natural killer cells are among the immune cells involved in the pathogenesis of lung cancer. The …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 2, 2022 · pp. 15–25 Read article
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Comparative Evaluation of Genotoxicity in Peripheral Blood Mononuclear Cells in Oral Precancer and Cancer Patients Using Single Cell Gel Electrophoresis
Abstract: In the present study the comet assay was performed in peripheral mononuclear cells to evaluate DNA damage among tobacco chewers and smokers. The assay provides a quick, accurate and sensitive way to detect various forms of DNA damage in individual cells. The study comprises 50 oral cancer patients, 12 oral submucous fibrosis patients and 10 healthy controls. The length of the comet tail was used to determine the level of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 2, 2022 · pp. 26–34 Read article
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Management of Polycystic Ovarian Syndrome (PCOS)
Abstract: The complex condition known as polycystic ovarian syndrome (PCOS) is characterized by chronic anovulation and hyperandrogenism. Depending on diagnostic criteria, 6–20% of females in reproductive age are afflicted. PCOS symptoms start to appear in the early pubertal years. Acne, anovulation, and irregular menstrual periods are features of PCOS and pubertal development in the average girl. The complex intertwined pathophysiology makes it difficult to identify the provoking factors. Most available scientific …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 2, 2022 · pp. 35–41 Read article
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A Short Review on Breast Fibroadenomas
Abstract: Breast Fibroadenomas are the most common type of benign breast lumps found mainly in adolescent women. These are unilateral, smooth, demarcated, rubbery, mobile, and painless masses. They are believed to be formed by the influence of changes in the female reproductive hormone, estrogen and sometimes the combination of both estrogen and progesterone which mainly occurs at the time of puberty. Fibroadenomas are mostly found in women till the age of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 2, 2022 · pp. 8–14 Read article