Research and Reviews : A Journal of Immunology
Volume 7, Issue 2 (2017)
Published
Table of contents
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Psychoactive and Physiological Homogeneity of Cannabis: A Literature Review: Actions of the Medical Plant that Takes Care of Itself
Abstract: Naturally occurring plants like Cannabis and the biologically ubiquitous alkaloids (e.g., morphine, quinine, and atropine) are composed of mostly physiological and psychoactive compounds. Extracts of the Cannabis plant are not alkaloid substances nor are they not related chemically to alkaloids, having no component nitrogen in their structures. Three species of Cannabis (marijuana) are recognized in scientific classifications: Cannabis sativa, Cannabis indicus and Cannabis ruderalis. Cannabis sativa is the species that …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 2, 2017 · pp. 1–4 Read article
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Next Generation Immunoassays for Infectious Diseases of Animals
Abstract: Veterinary diagnostics has an essential role to play in the management and control of infectious diseases. Immunodiagnostics originated towards the end of 19th century with the advent of agglutination- and precipitation-based serological techniques. Progress in immunodiagnostics during the 20th century is marked by development of complement fixation test, and later, fluoro-, radio- and enzyme-immunoassays during 1950s, 1960s and 1970s, respectively. Various immunodiagnostic test formats were improved for their performance characteristics …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 2, 2017 · pp. 22–43 Read article
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Recombinant Lactobacillus helveticus PJ4-Down Regulates TLR4 Mediated Inflammatory Responses in Sucrose Induced Diabetic Rats: A Novel Therapeutic Approach
Abstract: High sucrose diet (HSD) is known to induce type 2 diabetes. Recombinant Lactobacillus helveticus PJ4 was constructed to express the InuJ gene under the xylose promoter resulting in the secretion of inulosucrase enzyme in gastrointestinal tract which polymerizes the fructose moiety of sucrose to inulin type fructans. L. helveticus (pSLP-InuJ-Vhb) transformant (LHI) was intragastrically administered to rats fed with HSD diet. The composition of fecal microbiota and short-chain fatty acids …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 2, 2017 · pp. 44–65 Read article
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Immunomodulation in Viral Infections
Abstract: Several studies conducted over a period of two decades established that hypothalamic-pituitary-adrenocortical axis is activated during systemic viral diseases. Modulation of the Th1/Th2 balance may affect the susceptibility to or the course of infections. Reduction of T and B lymphocytes are reported during influenza virus infection. This modulation leads to limited immune response. The brain areas involved in the regulation of hypothalamic-pituitary-adrenocortical axis are affected during viral infection. Human immunodeficiency …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 2, 2017 · pp. 5–8 Read article
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Recent Advancement in Understanding the Aetiopathogenesis of Psoriasis: A Review
Abstract: Psoriasis is an immune-mediated inflammatory skin disease with periods of recurrence and remission. Various researches have globally explored the aetiopathogenesis of psoriasis but still it is not crystal clear. Abundant evidence suggest that dysregulation of immune cells in the skin, particularly keratinocytes, T cells, dendritic cells, natural killer cells, neutrophils, and macrophages play a vital role in the development of psoriasis. The combined effects of these cells explain most of …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 2, 2017 · pp. 9–21 Read article