Research and Reviews : A Journal of Immunology
Volume 2, Issue 3 (2012)
Published
Table of contents
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Measles Eradication by Vaccination: Opportunities and Challenges
Abstract: Measles is one of the vaccine preventable viral diseases that mainly occur in children. The disease was targeted for elimination by a vaccination program that was initiated three decades back. The measles death rate decreased by 74% from the year 2000 to 2010. This was short of targeted 90% mainly because of low vaccine coverage in some countries. Although, there is marked reduction in measles morbidity and mortality, still it …
Published in Research and Reviews : A Journal of Immunology · Vol. 2, Issue 3, 2012 · pp. 1–7 Read article
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Production of Single-domain Antibodies Library by Phage Display Technology
Abstract: Single-domain antibodies (dAbs) are synthesized from variable domain gene-segments of atypical camelid or shark “heavy chain antibodies” (HCAbs) by phage display technology. We have constructed a phage display library of > 5 × 107 dAb clones derived from HCAb genes in B lymphocyte repertoire of a lipopolysaccharide (LPS)-immunized Indian desert camel and isolated dAb-phage clones by panning of the library against LPS and Staphylococcus aureus exotoxins. Nucleotide and deduced amino-acid …
Published in Research and Reviews : A Journal of Immunology · Vol. 2, Issue 3, 2012 · pp. 8–13 Read article