Research & Reviews: A Journal of Drug Formulation, Development and Production
Volume 7, Issue 3 (2020)
Published
Table of contents
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A Novel Analytical Method for the Simultaneous Estimation of Remogliflozin and Metformin Hydrochloride
Abstract: Specific and novel strategy has been improved for assessment of Remogliflozin and Metformin hydrochloride in mass and plan and cleaning tests by UPLC-PDA. The scientific method was the phosphate Buffer (pH: 4.5): Acetonitrile, (60:40%, v/v) utilizing the spherisorb C18, 5 µm, 4.6 mm×150 mm insightful segment with investigation season of 5 min. The progression of versatile stage through section was 1.0 ml/min. The test volume was 10 µl. The discovery …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 1–15 Read article
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A Review on Repurposing Drugs for Treatment of Covid-19
Abstract: The newly emerged 2019 novel coronavirus is named as severe acute respiratory syndrome 2(SARS CoV-2). Till date, 1,757,393 cases have been observed in India and 37,452 deaths. COVID-19 has been now declared as pandemic and new treatments are urgently needed as we enter a phase beyond containment. In the absence of approved marketed drugs against coronavirus, the treatment and management of novel COVID-19 disease worldwide is a challenge. Developing new …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 16–22 Read article
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Improved Intestinal Absorption and Bioavailability Enhancement of Rosuvastatin Calcium via Proliposome Powder
Abstract: The main objective of the present study was to develop proliposomal formulations to enhance the oral bioavailability of rosuvastatin calcium by improving solubility, dissolution and/or intestinal permeability. Proliposomal powder formulations were prepared with drug varying the Phospholipon 90H and cholesterol ratio in the range of 1:0 to 1:1 using pearlitol SD200 as carrier by film deposition method. The prepared proliposomal powder was filled into capsules. The bioavailability enhancement of proliposomes …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 23–40 Read article
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An Overview on Potential of Piperine as a Bioavailability Enhancer
Abstract: Oral absorption of drug is significant issue particularly when the medication is ineffectively bioavailable, given for extensive stretches and costly. Bioenhancers can be characterized as substance elements, which when blended in with drugs advance and expand their bioavailability without indicating any synergistic impact with the medication. The elements like poisonousness, cost, helpless bioavailability and long haul organization of medications offer ascent to the need of bioenhancers which help conquer the …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 41–47 Read article
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Review on Drug Nanoparticles: Special Emphasis on Herbal Nanoparticals
Abstract: Nanoparticles have greater research horizon and smaller size ranging from 1 to 1000 nm. This is very small as compared to other particles. As their size is extremely small, so ultimately their route of administration and reaching to site of action becomes more convenient. These nano-scale particles can easily pass out the cell membrane such as blood brain-barriers. Nanoparticles are synthesized from various metals, polymers, microbes and even from plant …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 48–58 Read article