Research & Reviews: A Journal of Drug Formulation, Development and Production
Volume 1, Issue 1 (2014)
Published
Table of contents
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Development and Validation of a Gradient RP-HPLC Method for Quantitative Determination of Potential Manufacturing Impurities in New Drug Apronalide and Pharmaceutical Formulations
Abstract: Three impurities in apronalide drug substance were detected and quantified using a simple isocratic reverse phase HPLC method. The chromatographic separation was achieved on a Thermo Hypersil gold-CN, 100 A0 5 µm, and 250X4.6 mm using a mobile phase consisting of phosphate buffer (pH-4.6) - Methanol with UV detection at 210 nm and flow rate of 0.8 ml/min. The column temperature was maintained at 250C throughout the analysis. This method …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 1, Issue 1, 2014 · pp. 1–10 Read article
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In-house Preparation and Quality Control of a Unani Formulation
Abstract: Shangraf (Cinnabar) is used in traditional systems like Unani and Chinese system of medicine for the successful management of different diseases since time immemorial. In Unani system it is used in the form of kushta (Calcined product). This type of dosage forms are easily absorbed in the human body and are highly efficacious in action hence, are more popular and superior over other dosage forms. Kushta shangraf is highly reputed …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 1, Issue 1, 2014 · pp. 11–16 Read article
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Isolation, Identification and Molecular Cloning of Chitinase Gene in Bacteria Isolated from Crustacean Wastes
Abstract: This research envisaged cloning of genes encoding chitinases in bacteria isolated from crustacean wastes and its transformation in E.coli by TOPO cloning method for complete sequencing of partial gene. Chitin and chitinolytic enzymes are gaining importance for their biotechnological applications. Particularly, chitinases are used in both agricultural, industrial applications and also in human health care. The chitinases are present in chitin-containing microorganisms, bacteria and plants with a diversity of roles, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 1, Issue 1, 2014 · pp. 17–20 Read article