Research & Reviews: A Journal of Drug Design & Discovery
Volume 10, Issue 3 (2023)
Published
Table of contents
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Design And Evaluation Of Meloxicam Tablet For Colon Cancer
Abstract: Meloxicam, recognized as a preferential COX-2 inhibitor, has emerged as a promising chemopreventive agent for colorectal cancer. Leveraging its local and targeted action on the colon, Meloxicam proves to be a formidable component in the prevention of colorectal malignancies. This study aims to innovate by formulating and evaluating a targeted tablet delivery system for Meloxicam, emphasizing site-specific and instant drug release in the colon, thereby maximizing its therapeutic efficacy in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 3, 2023 · pp. 1–7 Read article
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Rivaroxaban: A Comprehensive Review of an Anticoagulant Revolution
Abstract: Rivaroxaban, a prominent direct oral anticoagulant (DOAC), has garnered attention for its pivotal role in preventing and treating thromboembolic diseases. Its introduction into clinical practice has marked a significant advancement in anticoagulant therapy. The mechanism of action of rivaroxaban involves selective inhibition of factor Xa, a crucial component in the coagulation cascade. This targeted approach distinguishes it from traditional anticoagulant and contributes to its efficacy. The significance of rivaroxaban lies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 3, 2023 · pp. 17–23 Read article
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Formulation and Development of Ibuprofen Floating Tablet
Abstract: The investigation focused on optimizing a gastric floating drug delivery system (GFDDS) for Ibuprofen tablets. It employed polymers like HPMC K4M and Carbopol 940 to improve Ibuprofen's bioavailability and therapeutic effectiveness. GFDDS, with lower bulk density than gastric fluids, remains buoyant in the stomach, extending gastric residence time. Compatibility assessments, via DSC analysis, indicated harmony between the polymers used, with no observed interaction between the polymer and the drug. The …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 3, 2023 · pp. 24–29 Read article
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Development Of Moisturizing Cream Incorporating From Sunflower
Abstract: The cultivated sunflower, scientifically known as Helianthus annuus annuus L. has a place to the class Helianthus, which has sixty-five species in add up to. This sunflower is local to America and is frequently developed within the Joined together States. As a member of the Asteraceae family, the cultivated sunflower exhibits a characteristic composite flower. The main objective of this study was to develop, formulate, and assess a moisturizing cream …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 3, 2023 · pp. 30–35 Read article
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Tridax Procumbens: Nature's Gift for Medicinal Benefits
Abstract: India possesses a diverse range of medicinal herbs due to its unique environmental conditions and varied seasons, which provide an ideal environment for the growth of numerous plant species. One such plant is the tridax procumbens, an annual herb that spreads widely and is native to India. Belonging to the Asteraceae family, it is known as "Ghamra" among the local population and referred to as "coat buttons" in English. Additionally, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 3, 2023 · pp. 8–16 Read article