Research & Reviews: A Journal of Bioinformatics
Volume 7, Issue 2 (2020)
Published
Table of contents
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Performance of Semantic Fluency tasks in Swahili-English Bilinguals
Abstract: AbstractVerbal fluency tests i.e. Semantic fluency tasks- are a neurophysiological test of verbal functioning, providing information on multiple cognitive processes used by an individual. Literature has shown that is it still unresolved as to if bilinguals show a specific linguistic disadvantage or advantage over certain cognitive processes in such tasks. This study aims to determine the performance of verbal fluency tasks i.e. semantic tasks amongst native primary language, Swahili (L1) …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 2, 2020 · pp. 1–8 Read article
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Efficient Identification of Complex Diseases Through Epistasis Computational Models: A Review
Abstract: AbstractGenome-Wide Association Studies (GWAS) identify and characterize the genes that are associated with human diseases. One of the significant ongoing researches in GWAS is to identify the disease susceptible genes through Epistasis. The gene that masks the effects of other genes is called Epistasis. The gene interacts with another gene is known as epistatic or genetic interactions (GGIs). GWAS identifies the genetic variants of Single Nucleotide Polymorphism and also the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 2, 2020 · pp. 21–32 Read article
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In Silico Identification of Small Molecules as Novel Coronavirus Protease Enzyme Inhibitors
Abstract: AbstractThe novel corona virus 2019 (COVID-19) is one of the global threats to the human civilization as it causes serious respiratory infection and multi-organ failure. Because of the absence of appropriate treatment protocol for 2019 novel corona virus, different methodologies are being tried in China, including drug repurposing. Recent discovery revealed the structure of novel corona virus main protease enzyme (Mpro) containing HIS41 and CYS145 amino acid residues present in …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 2, 2020 · pp. 33–43 Read article
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A Novel Approach of Protein Peptide Drug Delivery System
Abstract: Protein and peptides perform vital functions in body and are essential for life. They show various roles as therapeutic agents in treatment of cancer and diabetes. Various routes are available for the delivery of proteins and peptides such as oral route, transdermal route, pulmonary route, parenteral route, ocular route, nasal route, buccal route. However physicochemical properties of protein and peptides make them challenging for exogenous administration, especially in oral administration. …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 2, 2020 · pp. 44–59 Read article
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A Quasi Experimental Study to Assess the Effectiveness of Planned Health Teaching on the Knowledge Regarding Self-Care among Type II Diabetes Mellitus Patients in Selected Hospitals of Nasik city
Abstract: AbstractA quasi experimental study was conducted to assess the knowledge regarding self-care among type II Diabetes mellitus patients in selected hospitals of Nasik city.” The questionnaires were distributed to patients for assessing the knowledge regarding self-care of type II Diabetes mellitus. The pilot study was conducted on 3samples & was found feasible. Final study was carried out on 30 samples. The data collected was analyzed using descriptive and inferential statistics …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 2, 2020 · pp. 9–20 Read article