Research & Reviews: A Journal of Bioinformatics
Volume 7, Issue 1 (2020)
Published
Table of contents
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Molecular Docking Approach on Thiazolidinedione Analogs as HIV-1-RT Inhibitors
Abstract: Potentially life threatening condition due to chronic syndrome caused by human immunodeficiency virus (HIV) is known as Acquired immunodeficiency syndrome(AIDS).Virus weakens the immune system of human being and body’s ability to fight against the organism, thereby causing the disease. When a person becomes infected with HIV, the virus attacks and weakens the immune system. In the given study, molecular docking study was performed on 30polysubstitutedThiazolidinedione (TZD) analogs as HIV-1 reverse …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 1, 2020 · pp. 1–6 Read article
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Prevalence of Stress in Patients Attending Homeopathic General Outpatient Department in Government Dispensaries at Siliguri, West Bengal, India: A Multicentric Cross-Sectional Observational Study
Abstract: Background: The overall weighted prevalence of depressive disorders is 2.7%, Generalized Anxiety Disorder (GAD) is 0.6%, Post-Traumatic Stress Disorder (PTSD) is 0.2% whereas the prevalence of Alcohol Use Disorders is 4.6%. Objectives: To assess the prevalence of moderate-to-severe stress in patients attending homeopathic general outpatient department (OPD) of five hospitals in three months by using Patient Stress Questionnaires (PSQ). Design: It was a multicentric, cross-sectional observational study. Setting: The present …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 1, 2020 · pp. 14–22 Read article
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Relation of p53 Codon 72 Polymorphism with Breast Cancer Risk in DPR Korea Women
Abstract: Background: The p53 codon 72 polymorphism (rs1042522) is a single-nucleotide polymorphism (SNP) in exon 4 of p53 gene, resulting in the expression of either arginine (Arg), which encodes CGC, or proline (Pro), which encodes CCC. The p53 codon 72 polymorphism have been implicated as a risk factor for various cancers including breast cancer. We have investigated the association of the Arg/Pro polymorphism at codon 72 of p53 gene with breast …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 1, 2020 · pp. 23–30 Read article
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Databank on Phytochemistry and Phytotherapy
Abstract: Presented review serves as an example of the application of Excel-VBA on huge data amounts considering the areas of world-wide Ethnopharmacology, Pharmacognosy together with modern identification tools within Phytochemistry. In recent years, modern drug design has returned back to nature, rather applying guidance achieved from herb remedies valid during centuries. The databank established of information of 200 medicinal plants from all parts of the globe, comprises now of over 4700 …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 1, 2020 · pp. 31–51 Read article
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Design and Simulation Study of Drug-Eluting Stents for Treating Hepatic Artery Stenosis Post Liver Transplantation
Abstract: Hepatocellular carcinomais amongst the most common cancers worldwide, accounting for nearly 1 million deaths annually. Early diagnosis would help in treating with chemotherapy and ablative techniques but with most of the liver being affected; only transplantation would be a treatment of choice. Apparently, after orthotopic liver transplantation (OLT), an issue of hepatic artery stenosis (HAS) can occur which would later lead to hepatic artery thrombosis (HAT), with subsequent liver failure …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 1, 2020 · pp. 7–13 Read article