Research & Reviews: A Journal of Bioinformatics
Volume 1, Issue 3 (2014)
Published
Table of contents
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In silico 3D Structure Modeling and Analysis of Galactoside 2-alpha-L-fucosyltransferase 1
Abstract: A rare group of blood known as Bombay blood group was discovered in Mumbai formerly known as Bombay more than five decades ago, which lacks A, B, AB and O type. A theoretical model of human Galactoside 2-alpha-L-fucosyltransferase 1/FUT gene is predicted. The model was generated by application of homology modeling and structure prediction approaches. As the template homology to the query sequence is too low a multiple online modeling …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 1, Issue 3, 2014 · pp. 1–11 Read article
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Insilico Approach to Inhibit Over Expression of CaSm Gene to Arrest Over Expressed Human LSm1 Protein in Pancreatic Carcinoma Cell
Abstract: Small nuclear ribonucleoproteins (snRNPs) are particles that are found in the nucleus of eukaryotic cells. They consist of one RNA (snRNA) associated with one or more proteins. snRNPs are involved in a wide variety of functions including pre-mRNA splicing (e.g., U1, U2, U4–6, U11, U12, U4ATAC, U6ATAC snRNPs and transspliced leader RNPs), histone mRNA 39 end processing (U7 snRNP). The snRNA U6 (unlike U1, U2, U4 and U5) does not …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 1, Issue 3, 2014 · pp. 12–23 Read article
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Insilico Study Showing the Chemical Properties and Interaction between Auxin-Binding Protein and Auxin-Responsive GH3-8 Protein in Rice
Abstract: Auxin plays an important role in the plant growth. There are different auxin binding and auxin responsive proteins which bind and interact with auxin hormone and helps for plant development. Two different rice proteins considered for study, one protein binding to auxin and another is the auxin responsive protein. The Nuclear magnetic resonance (NMR) crystallographic structures of both the proteins are not available at Protein Data Bank (PDB). So the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 1, Issue 3, 2014 · pp. 24–30 Read article
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Insilico 3D Structure Modeling and Docking to Find Potent Inhibitors for Thrombocytopenia
Abstract: Lots of people are getting affected by various kinds of auto-immune disease in their day to day life and thrombocytopenia is one of them, which occurs due to lack of thrombocytes or platelets. Various kinds of vaccines, drugs are used to stop the disease, but the effect varies from person to person depending upon the immune system. In thrombocytopenia disease the integrin beta protein of human affects the person’s own …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 1, Issue 3, 2014 · pp. 31–40 Read article
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Comparative Structural Analysis of Dep1 Protein in Oryza Sativa
Abstract: Dense erect panicle protein is an important protein of Oryza sativa which helps in high grain production. The objective is to find out the structure of protein and to represent the best 3D model by using insilico analysis. In Oryza sativa the dep1 is homologous to crystal structure of expb1 of zea mays, a beta-expansion and group-1 pollen allergen from maize which is responsible for plant growth and development. The …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 1, Issue 3, 2014 · pp. 41–45 Read article