5 publications
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Herbal Immuno-modulators- Pros and ConsBy Blessy Jacob, NaveenKumar M, Subha Deepa, D Visagaperumal, Vineeth Chandy
Abstract: Recently, there has been a greater global focus on plant research, and a ton of data has accumulated to show the enormous potential of the medicinal plants used in various traditional systems. In actual practise, the majority of immunostimulants and immunosuppressants are cytotoxic medications with substantial side effects. In treating immune-related disorders, there is growing interest in using herbal medicines as multi-component agents to modulate the complex immune system and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 10, Issue 3, 2023 · pp. 22–29 Read article →
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NANOBOTS - The Artificial BloodBy Blessy Jacob, Madhavi V L, Vineeth Chandy
Abstract: Artificial blood is simulated to biological blood to higher extent where it is expected to be used to imitate and accomplish some very important functions of natural blood. Thus, nanobots can be a good alternative to blood transfusion in case of medical emergency too. They have several advantages like possibility of highly targeted delivery which will ultimately decrease the side effects and the need for invasive steps combinedly NANOBOTS—The artificial …
Published in Trends in Drug Delivery · Vol. 5, Issue 2, 2018 · pp. 20–22 Read article →
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Ludiflash—A Novel Excipient for Patient Friendly Dosage FormBy Blessy Jacob, Lata K. Bisht, Vineeth Chandy
Abstract: Consumers want a pleasant-tasting and fast-acting tablet that can be taken anywhere, anytime without the need of water. They want such a tablet that completely disintegrates within moments, with no bitterness or chalky aftertaste. FDTs fast disintegrating tablets are the dosage form which will disintegrate in mouth within seconds without need of water. This type of property in dosage form can be attained by addition of different varieties of excipients. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 2, 2017 · pp. 5–7 Read article →
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3D QSAR Studies of 2,3-Disubstituted Quinazolin Phenyl Acetic Acid Derivatives as Antimicrobial AgentsBy Blessy Jacob, Lata K. Bisht, Vineeth Chandy
Abstract: Quantitative structure activity relationship (QSAR) studies have been performed on series of31 compounds of 2,3-disubstituted quinazolin phenyl acetic acid derivatives withantimicrobial activity using Chemoffice version 8.0 software. The QSAR models have beendeveloped by using multiple linear regressions in order to identify descriptors, which areactually focusing towards the biological activity. Leave one out (LOO) method was employedin cross validation analysis to validate the developed model. The best predictive QSAR modelderived, had …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 2, 2017 · pp. 4–7 Read article →
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Quantitative Structure Activity Relationship Studies of Some New 4-Thiazolidinone Derivatives as Antimicrobial AgentsBy Blessy Jacob, Lata K. Bisht, Vineeth Chandy
Abstract: In the present study, quantitative structure activity relationship (QSAR) studies have beenperformed on series of 24 compounds of 4-thiazolidinone derivatives with antimicrobialactivity using Chemoffice version 8.0 software. The QSAR models have been developed byusing multiple linear regressions in order to identify descriptors, which are actually focusingtowards the biological activity. Leave one out (LOO) method was employed in crossvalidation analysis to validate the developed model. The best predictive QSAR model derived,had …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 2, 2017 · pp. 1–3 Read article →