1 publication

• Published Subscription 31 Oct 2018

  Synthesis and Biological Evaluation of Mannose Thiazolidinones

  By Avula Srinivas, Md Aleempasha, V Sudhaker Reddy, S Srinivas

  Abstract: In a one pot procedure, a series of novel mannose thiazolidinone derivatives 4a–g and 5a–g were prepared by condensation of (3aS, 4S, 6S, 6aS)-6-methoxy-2,2-dimethyltetrahydrofuro [3,4-d][1,3]dioxole-4-carbaldehyde-3 with mercapto acids and primary amines in presence of ZnCl2 under both micro wave irradiation and conventional heating conditions. Compound-3 was prepared from Methyl di acetone D-Mannose with primary acetonide deprotection and with oxidative cleavage. Characterization of new compounds has been done by means of …

  Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 2, 2018 · pp. 38–46 Read article →