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• Published Subscription 30 Jan 2019

  Synthesis and Chemical Characterization of Benzopyran Derivatives Fused to Pyrimidine Moiety

  By Bibi Fareesa Banu, Y. Rajesh Babu, Ausaf Butool, Tuba Khan

  Abstract: In an attempt to find a new class of antimicrobial agents, a series of fused benzopyran derivatives containing pyrimidine moiety were prepared via the reaction of 2-(1h-benzo[d] imidazol-2-yl acetonitrile with 2-amino-3-(1h-benzo[d] imidazol-2-yl)-4-phenyl-4h-chromen-7-ol in the presence of piperidine and anhydrous zinc chloride. The target molecules were also synthesized using interchange component strategy. These compounds were screened for their antibacterial activity against gram-positive bacteria (Staphylococcus aureus and Streptococcus pyogenes), gram-negative bacteria (Pseudomonas …

  Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 3, 2018 · pp. 11–23 Read article →