2 publications
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Published Subscription
Improved Intestinal Absorption and Bioavailability Enhancement of Rosuvastatin Calcium via Proliposome PowderBy Smitha Gandra, S. Sharath C. Reddy, S. Nagasri, V. Vyshnavi, Raju Jukanti
Abstract: The main objective of the present study was to develop proliposomal formulations to enhance the oral bioavailability of rosuvastatin calcium by improving solubility, dissolution and/or intestinal permeability. Proliposomal powder formulations were prepared with drug varying the Phospholipon 90H and cholesterol ratio in the range of 1:0 to 1:1 using pearlitol SD200 as carrier by film deposition method. The prepared proliposomal powder was filled into capsules. The bioavailability enhancement of proliposomes …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 23–40 Read article →
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Published Subscription
A Review on Natural Radio-protective AgentsBy Smitha Gandra, Shilpi Kondaskar, Swapna Gawai
Abstract: AbstractRadioprotectors play crucial role in safeguarding biological system from various damages to DNA (Deoxyribonucleic acid), protein molecules, lipids by peroxidation as well as hematopoietic, gastrointestinal, reproductive and central nervous system exposed to radiation dose especially against radiation injury in cancer survival patients undergoing radiotherapy. As over 40% patients require this therapy, during the treatment where ionizing radiation is used to shrivel tumors and exterminate cancer cells by disrupting their DNA. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 2, 2020 · pp. 20–31 Read article →