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Study on Efflux Pump Inhibition Activity of Marine Actinomycetes against Oflaxcin Resistsnt M. tuberculosisBy Gajalakshmi P, Raja A, Arthur James R
Abstract: Studies were conducted to isolate marine actinomycetes active against oflaxcin resistant M. tuberculosis. Out of 25 actinomycetes isolates designated as ECRMP 4 showed potent antimycobacterial activity against all three tested Mycobacterial strains. Representative bioactive isolate was characterized using phenotypic property and identified as Micropolyspora sp. The zone of inhibition was 20 ± 0.1 mm (62% RIZD) against M. tuberculosis and 18 ± 0.6 mm (100% RIZD) against OFLR M. tuberculosis. …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 4, Issue 2, 2014 · pp. 25–30 Read article →