2 publications
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Published Subscription
Cyclooxygenase 3 Inhibition: A Probable Mechanism of Acetaminophen in Human: A ReviewBy Iswar Hazarika, Panner Selvam
Abstract: The key rate-limiting step in prostanoid and thromboxane biosynthesis is catalyzed by Cyclooxygenases (COXs) and is the target of nonsteroidal anti-inflammatory drugs (NSAIDs). Until recently, the existence of only two isoforms: COX-1 and COX-2; remained under debate as the anti-pyretic and analgesic property of acetaminophen (paracetamol) could not be explained by mere COX-1 or COX-2 blockades. A novel COX-1 splice variant termed COX-3, sensitive to acetaminophen, was recently discovered in …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 3, 2015 · pp. 23–29 Read article →
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Published Subscription
Anti-Ulcer Activity of Methanolic Extract of Mucuna Pruriens Seed on Indomethacin Induced Ulcers in Albino RatsBy Iswar Hazarika, Panner Selvam, Anju Das
Abstract: The present study was intended to investigate and evaluate the antiulcer activity of the methanol seed extract of Mucuna pruriens using indomethacin induced ulcer in albino rats and to determine its link between oxidant or antioxidant parameter. The extract of Mucuna pruriens was tested on indomethacin induced gastric ulcer in albino rats. The antiulcer activity of high dose (400 mg/kg) and low dose (200 mg/kg) of ethanolic extract of Mucuna …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 5, Issue 2, 2015 · pp. 1–8 Read article →