2 publications
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Published Subscription Review Article
Advanced Techniques in Filler Layering for the Malar Region: Implications for Cellular Integrity and Long-Term OutcomesBy Soumitra Das, Mekkanti Manasa Rekha
Abstract: Objective: This review investigates advanced filler layering techniques for the malar region, focusing on cellular integration, collagen remodeling, hydration dynamics via aquaporin channels, genetic responses, and filler performance over time. Emphasis is placed on high-density HA fillers (Lyft, Voluma, Volift, and Volux), examining cellular-level mechanisms, genetic interactions, and the role of key pathways (TGF-β, ERK/MAPK, AQP3) in long-term outcomes. Methods: A systematic review was conducted, focusing on genetic, cellular, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 10–19 Read article →
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Published Subscription Review Article
A Short Review on Long-Term Effects of Botox on Neuronal Sprouting: Mechanisms and Its Clinical ImplicationsBy Soumitra Das, Mekkanti Manasa Rekha
Abstract: Botulinum toxin (Botox) is extensively used for its ability to induce temporary muscle paralysis through inhibition of acetylcholine release at neuromuscular junctions. While its short-term effects are well documented, emerging evidence suggests that chronic use of Botox may trigger neuronal sprouting, a process that could have significant long-term implications. This review synthesizes current research on the mechanisms by which Botox induces nerve sprouting and evaluates the clinical outcomes associated with …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 72–87 Read article →