STM Journals Peer-reviewed research from Consortium e-Learning Network

2 publications

  • Published Subscription Original Research Special issue

    Synthesis and Characterization of pH-Sensitive Poly (N-isopropylacrylamide-co-acrylic Acid) Hydrogels for Controlled Release of Doxorubicin

    By Akshay Kumar K.S., Suhas Narayan Sakarkar, Vijeta Bhattacharya, Maneshwar Thippani, L. Karpagavalli, Deepha V., Shiny George, Nitin S. Bhajipale, Manish R. Bhise

    Abstract: pH-responsive polymeric hydrogels have attracted significant attention as intelligent biomaterials for site-specific and controlled drug delivery in cancer therapy due to their ability to respond to the acidic tumor microenvironment. In the present study, poly (N-isopropylacrylamide-co-acrylic acid) [P(NIPAM-co-AAc)] hydrogels were synthesized via free radical copolymerization and systematically characterized to evaluate their suitability for controlled delivery of doxorubicin, a widely used chemotherapeutic agent. The copolymer hydrogels were prepared using N-isopropylacrylamide and …

    Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 449–458 Read article

  • Published Subscription Original Research Special issue

    Structure–Property Relationships in Poly (N isopropylacrylamide) Hydrogels: Toward Thermoresponsive Polymer Composites

    By Nadeem Hasan, Lalit Mohan Nainwal, Poonam Arora, Gopal Dilip Wagh, Mrinal Kanti Bhoumik, Anuja P. Bhosale, Rajeeva Bhaskar, Amit Kumar Singh, Manish R. Bhise

    Abstract: Poly(N-isopropylacrylamide) (PNIPAAm) hydrogels can shift from solid to gel and back again at body temperature. Due to their lack structural integrity, thermal stability, and mechanical strength, they are difficult to use. This study mixed PNIPAAm with biocompatible fillers like chitosan and silicon nanoparticles to create hydrogels with superior structure-property correlations. Free radical polymerization with ammonium persulfate/TEMED initiator and N,N′-methylenebisacrylamide crosslinker produced the composites. Scanning electron microscopy showed a denser, interconnected …

    Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 884–895 Read article

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