2 publications

• Published Subscription Original Research Special issue 26 Mar 2026

  Evaluation of Mucoadhesive Polymers for Nasal Delivery of Herbal Bioactives

  By Dattatray S. Ghotekar, Ramandeep Kaur, Rasika Manoj Rewatkar, Ishita Sharma, Sujata V. Wankhede, Kavitha C, Sanjeev Kumar, Raosaheb Y. Ghegade, Rishi Pal

  Abstract: A study assessed mucoadhesive polymers for intranasal herbal bioactive administration with higher residence time and mucosal permeability. Chitosan, Carbopol® 934P, and HPMC K15M were utilized to manufacture mucoadhesive nasal gels with standardized herbal bioactive fractions. Formulations were examined for pH, viscosity, spreadability, drug content, mucoadhesive strength, in-vitro release, ex-vivo penetration, and short-term stability. All formulations demonstrated a suitable pH for nasal usage and uniform drug content (97.48 ± 1.12% to …

  Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1680–1689 Read article →

• Published Subscription Original Research Special issue 20 Mar 2026

  Development of Biodegradable Poly (Lactic-Co-Glycolic Acid) (PLGA) Nanoparticles for Sustained Release of Insulin

  By Amit Kumar Singh, Anuradha Singh, Raosaheb Y. Ghegade, Shubham Sharma, Chetna Devkar, Kavitha C, Manisha S Nangude, Anagha Amit Sarvadnya, Mrinal Kanti Bhoumik

  Abstract: This research outlines the creation of biodegradable composite nanoparticles made from poly (lactic-co-glycolic acid) (PLGA) designed for the sustained release of insulin. The emphasis is on the interactions between the polymer and the drug at the interface, along with the dynamics of the release matrix. The in vitro release kinetics, surface morphology, encapsulation efficiency, particle size, and polydispersity of insulin-loaded PLGA nanoparticles were analyzed following their production via a double …

  Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1690–1699 Read article →