2 publications
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Published Subscription
DESIGN AND EVALUATION OF SANDWICH TABLET FOR SUSTAINED RELEASE DRUG DELIVERY OF DICLOFENAC SODIUM.By JAIMIN B. PATEL, MR. BHAVIN BHIMANI, DR. HIREN KADIKAR, DR. UPENDRA PATEL
Abstract: The objective of this experiment was to create bilayer sandwich pills using the model medication diclofenac. A lengthy duration of action is provided by the combination of an immediate and sustained release layer, which lengthens the effect in the body. Diclofenac sodium has excellent antipyretic, analgesic and anti-inflammatory effects. A super disintegrating carboxyl agent, such as methyl cellulose, is used for the quick release layer of a bilayer sandwich tablet …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 2, 2023 · pp. 1–8 Read article →
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Published Subscription
Formulation And Evaluation Of Captopril Sustained Release Tablet By Qbd Approach.By JAIMIN B. PATEL, DR. PARESH PRAJAPATI, DR. RAKSHIT SONALPAL, MR. BHAVIN BHIMANI, DR. UPENDRA PATEL
Abstract: The purpose of present study was to formulation and evaluation of Captopril sustained release tablet by QbD approach using size expanding polymer and cross linker. Captopril is a ACE inhibitor use in treatment of mild to moderate hypertension. Captopril having biological half-life of 2 hrs. The drugs gets degrade as its goes to higher pH, so we selected size expanding GRDDS. In formulation development study by using QbD, we found …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 1, 2023 · pp. 64–73 Read article →