STM Journals Peer-reviewed research from Consortium e-Learning Network

4 publications

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    Pharmaceutical Cocrystals of Pain Relieving Drugs

    By Bhupinder Singh Sekhon

    Abstract: Cocrystallisation of two components into one crystal form can enhance the solid-state properties of drug compounds. Cocrystals are considered as the next generation modified-active pharmaceutical ingredients with improved physical-chemical, (aqueous solubility, dissolution, hygroscopicity, bioavailability, stability, increase of melting point, purity of an active pharmaceutical ingredients (API), intellectual property positions) and pharmacokinetic properties. Cocrystal formation may overcome dissolution problems of highly lipophilic APIs because the new crystalline lattice being formed often …

    Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 1, 2015 · pp. 16–27 Read article

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    Agricultural Residues as Pharmaceutical Excipient

    By Bhupinder Singh Sekhon

    Abstract: Excipients development has become a core area of research in pharmaceutical drug delivery. Agricultural residues and natural sources represent a potential source of inexpensive pharmaceutical excipients. Pharmaceutical excipients have vital roles in drug formulations and dosage forms and are used as thickeners, gelling, bulking and water retention agents, fillers, binders, disintegrants, lubricant and/or glidant, flavours and sweeteners. Microcrystalline cellulose (MCC), a very important directly compressible excipient widely used in pharmaceutical …

    Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 3, 2014 · pp. 1–7 Read article

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    Nanoinformatics: An Overview

    By Bhupinder Singh Sekhon

    Abstract: Nanoinformatics uses informatics techniques to (i) collect, (ii) process, (iii) store, and (iv) retrieve information on nanoparticles/nanomaterials/nanodevices and their potential applications in health care. Nanoinformatics assists to develop new computing applications to accelerate research and development in nanomedicine. In this context, it is playing an important role in acquiring relevant data and information, conceptually organizing information for conversion to knowledge, and developing computing applications that are based on important parameters …

    Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 1, 2014 · pp. 21–25 Read article

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    Edible Transgenic Plant Vaccines – An Overview and Update

    By Bhupinder Singh Sekhon

    Abstract: Normal 0 false false false EN-IN X-NONE X-NONE Plants are used as bioreactors to express antigenic molecules to be administered as vaccines. Edible transgenic plant vaccines (ETPV) are plant materials (recombinant protein subunit vaccines), and the edible plant tissue functions as an oral vaccine. ETPV are mucosal targeted vaccines where stimulation of both systematic and mucosal immune network takes place and these diminish the utilization of conventional animal or bacterial …

    Published in Research and Reviews : A Journal of Biotechnology · Vol. 1, Issue 2, 2011 Read article

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