2 publications
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Published Subscription
Friendly and Efficient Synthesis of Chalcone Derivatives under Solvent-Free ConditionBy Mohamad F. Ali, Abdulrahim M. Khlafulla
Abstract: A series of various chalcone derivatives were synthesized using solvent free technique by grinding different substituted benzaldehyde, acetophenone and NaOH pellets at room temperature, and same reactions were carried out under solvent condition (50% EtOH). The reaction time needed to synthesize desired chalcones was 15–45 min; and 13 h stirring in the presence of solvent. All compounds were identified by comparison of their melting points with that of the substrates; …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 1, 2016 · pp. 17–24 Read article →
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Published Subscription
Comparison Study of the Reactivity of 2-Acetyl Heterocyclic Compound toward Aldol Condensation with Benzaldehyde DerivativesBy Abdulrahim M. Khlafulla, Mohamad F. Ali
Abstract: Some new chalcones have been synthesized by condensation of 2-acetyl pyrrol, 3-acetyl pyridine and 3-acetyl indole with various aromatic aldehydes in 25% alcoholic alkali. The synthesized compounds were identified by spectral and physical methods. From the time of reactions and the yield of the products, we can state that there were some obvious differences in the reactivity between the heterocyclic compounds used. Keywords: Reactivity, chalcone, aldol condensation, heterocyclic compounds, benzaldehyde …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 1, 2016 · pp. 34–38 Read article →