PolyPhen

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• Published Subscription 12 Dec 2018

  Comprehensive In silico Analysis of Single Nucleotide Polymorphisms (SNPs) in Human BDNF Gene

  By Shovit Ranjan, Praveen Kumar Sharma

  Abstract: Since a number of single nucleotide polymorphisms (SNPs) are associated with the BDNF gene mutations involved in different diseases. Hence, it is important to find out the probable functional SNPs before planning a larger population study. So, to look out for the functional nsSNPs (non-synonymous single nucleotide polymorphisms) in BDNF gene, existing data present in the dbSNP database and different bioinformatics tools like SIFT, PolyPhen, nsSNPAnalyzer, F-SNP, I-mutant, Pymol were …

  Published in Research and Reviews : A Journal of Life Sciences · Vol. 8, Issue 3, 2018 · pp. 128–139 Read article →