Mycobacterium tuberculosis complex

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• Published Subscription Original Research 17 Feb 2025

  First Insights into Whole Genome Sequencing of the Mycobacterium tuberculosis Complex: Molecular Diversity and Drug Susceptibility Patterns in Senegal

  By Abdou Padane, Seyni Ndiaye, Malle Gueye, Mamadou Nda, Marièma Sarr, Aminata Mboup, Marilyne Aza-Gnandji, Darrel Ornelle Elion Assiana, Ndèye Astou Dabo, Yacine Amet Dia, Mame Sokhna Gueye, Ndeye Ndack Cissé, Bineta Diouf, Joséphine Khady Badiane, Papa Alassane Diaw, Abdoulaye Samba Diallo, Ousmane Diop, Ousmane Diouf, Raghavendra Amachawadi, Fatoumata Ba, Yacine Mar Diop, Souleymane Mboup, Abdoulaye Leye Sarr

  Abstract: Background: We conducted a bibliographic analysis of the Mycobacterium tuberculosis complex (MTBC) in sub-Saharan Africa, which included the analysis of 8,139 genomic sequences from 34 of the 49 sub-Saharan African countries. Notably, only one complete sequence from Senegal was identified, which had been generated in the United States. Our primary objective was to utilize whole genome sequencing (WGS) to detect resistance in anti-tuberculous strains of the MTBC in Senegal. This …

  Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article →