Diagnostic challenges
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Atypical Psychiatric Presentations of Autoimmune Encephalitis: A Case Series and Proposed Clinical Approach to Diagnosis
Abstract: Background: knowledge and detection of seronegative autoimmune encephalitis (AE) is growing rapidly, but typical psychiatric presentations risk misdiagnosis or delay in diagnosis with worse prognostic outcomes. Paraclinical markers are useful when positive, and integral to the current diagnostic framework yet have limited sensitivities leaving an unknown percentage of patients without diagnosis or treatment. Cases not meeting diagnostic criteria pose a particular clinical challenge regarding diagnosis and treatment decision making and …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 12, Issue 2, 2022 · pp. 26–37 Read article