Crohn’s Disease

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• Published Ahead of print Open access Article 7 Jan 2023

  Synthesis and Evaluation of New Coumarin Derivatives for Inflammatory Bowel Disease Against DSS-Induced Acute Ulcerative Colitis Mice Model

  By Priyanka Bajpai, Om Prakash, Amresh Gupta, Chandra Bhushan Tripathi

  Abstract: Objective: The discovery of the now numerous mouse models of intestinal inflammation has increased our understanding of the intestinal inflammation that occurs in inflammatory bowel disorders (IBD). This study aimed to investigate the use of a standardized animal model subjected to coumarin derivative treatment, and the action of synthesized molecule administration of dextran sodium sulphate (DSS)- induced colitis in experimental mice. Materials and Methods: We generated a variety of unique …

  Published in Journal of Modern Chemistry & Chemical Technology Read article →