Claisen –Schmidt condensation
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Synthesis and Evaluation of Chalcone Derivatives and Schiff bases derivatives as Antibacterial
Abstract: AbstractSix substituted chalcones have been synthesized by condensing benzaldehyde derivatives with acetophenone in dilute ethanolic sodium hydroxide solution at room temperature according to Claisen-Schmidt condensation. In addition, four of Schiff bases have been prepared via imine condensation between substituted benzaldehyde firstly with (3) 2-aminophenol, secondly, with phenylhydrazine. Moreover, study the efficient of synthesized compounds as antibacterial agents were evaluated. The structures of the synthesized compounds were confirmed by the melting …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 9, Issue 3, 2018 · pp. 1–7 Read article