Carbopol 940

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• Published Subscription 15 Feb 2024

  Formulation and Development of Ibuprofen Floating Tablet

  By Fathima Fabina, Syam Prasad PS, Fathima Hanan, Fathima PM, Dr.Ibrahim Afsal

  Abstract: The investigation focused on optimizing a gastric floating drug delivery system (GFDDS) for Ibuprofen tablets. It employed polymers like HPMC K4M and Carbopol 940 to improve Ibuprofen's bioavailability and therapeutic effectiveness. GFDDS, with lower bulk density than gastric fluids, remains buoyant in the stomach, extending gastric residence time. Compatibility assessments, via DSC analysis, indicated harmony between the polymers used, with no observed interaction between the polymer and the drug. The …

  Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 3, 2023 · pp. 24–29 Read article →