caffeic acid
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Effect of Caffeic Acid on Glutathione Metabolism of MCF-7 and MDA MB-231 Breast Cancer Cells
Abstract: Increasing incidences of breast cancer at alarming rates with treatment strategies having an overall detrimental effect on the patients led to investigating the potential of phytochemicals as anti-tumorigenic agents. Caffeic acid, an antioxidant and anti-tumorigenic phytochemical, has been tested on MCF-7(hormone responsive) and MDA MB-231(hormone-independent) breast cancer cell lines. Alterations in the levels of intracellular glutathione (GSH) in both cell lines due to exposure to the drug are the primary …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 1, 2022 · pp. 14–22 Read article