Breast carcinoma
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A Short Review on Breast Fibroadenomas
Abstract: Breast Fibroadenomas are the most common type of benign breast lumps found mainly in adolescent women. These are unilateral, smooth, demarcated, rubbery, mobile, and painless masses. They are believed to be formed by the influence of changes in the female reproductive hormone, estrogen and sometimes the combination of both estrogen and progesterone which mainly occurs at the time of puberty. Fibroadenomas are mostly found in women till the age of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 2, 2022 · pp. 8–14 Read article
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Role of Transcription factor AP-1 in Breast carcinoma
Abstract: Breast cancer is a major health problem of today. Transcription factor is nothing but protein that is needed for transcription. Activator protein-1 (AP-1) is a transcription factor of complex oncogene proteins (Jun and Fos). Fos and Jun family participate in many cellular processes which includes proliferation, differentiation and carcinogenesis. Therefore, this study has been designed to study level of transcription factor AP-1 in breast carcinoma. The study was carried on …
Published in Research and Reviews: A Journal of Health Professions · Vol. 9, Issue 2, 2019 · pp. 22–28 Read article
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Role of Nitric Oxide in Platelets of Breast Carcinoma
Abstract: Breast cancer is a disease of multifactorial origin; it is seen frequently in women of older age, having family history, affluent society, late age of marriage and first childbirth, early menarche, late menopause, and nulliparity. Oxidative stress results when balance between reactive oxygen species (ROS) production and antioxidant defence is lost which result in mutations, sister chromatid exchanges, cytotoxicity, carcinogenesis etc. Clinical, experimental and epidemiological studies suggest that free radicals …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 2, 2019 · pp. 25–29 Read article