antifungal agents
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Design, Synthesis, and in vitro Evaluation of Novel Benz/Imidazole-2-acetonitrile Derivatives as Antibacterial and Antifungal Agents
Abstract: Benzimidazole is a pharmaceutically important compound. In this research, we were able to prepare several heterocyclic derivatives from it by first preparing a new azo derivative ZH through a reaction of 3-aminoacetophenone with benzimidazole-2-acetonitrile. This azo derivative was then introduced via a condensation reaction with aromatic amine derivatives, resulting in the preparation of two Schiff base derivatives Z1 and Z2. From these bases, six and seven membered heterocyclic derivatives were …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 2, 2026 · pp. 53–87 Read article
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Characterization of Synthesized Heterocyclic Oxadiazole Derivatives Using Mass, UV, IR, and NMR Spectroscopy, Among other Spectroscopic Techniques: Review
Abstract: The current study synthesized and assessed 3-heteroarylazo 4-hydroxy coumarin derivatives' initial antibacterial activities in vitro against four distinct pathogenic bacterial strains, including Pseudomonas aeruginosa, Bacillus subtilis, Escherichia coli, and Staphylococcus aureus. Ampicillin, a common medication, was used to compare each compound's antibacterial properties. UV, IR, 1H NMR, mass spectroscopy, and X-ray diffraction examinations were used to analyze the compounds. By using UV–vis spectra, the solute-chromic behavior of these compounds was …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 1, 2023 · pp. 28–33 Read article