Amyloid cascade hypothesis
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The Pathophysiology, Diagnosis and Some Management Approaches of Alzheimer’s Disease: An Overview
Abstract: Alzheimer’s disease is the greatest mutual cause of dementia globally, with the occurrence ongoing to grow in part because of the aging world populace. This neurodegenerative disease process is categorized characteristically by 2 mark pathologies: β-amyloid plaque deposition and neurofibrillary masses of hyperphosphorylated tau. Diagnosis is grounded on biomarkers restrained in vivo even beforehand the onset of clinical dementia symptoms. No solitary biomarker can by itself properly diagnose AD. A …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 2, 2023 · pp. 1–17 Read article