4?-methylenedioxy
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3′,4′-Methylenedioxy Moiety Containing Murrayanine Based Chalcone as Emerging Anti-inflammatory Agent
Abstract: Natural products are the emerging compounds for treating a wide variety of ailments. In a recent trend, rational semi-synthesis remained an impressive approach for developing inhibitors with pronounced activity. 3′,4′-methylenedioxy have been found to be present in a variety of compounds expressing anti-mycobacterial, anti-inflammatory, anti-cancer, analgesic, anti-pyretic, etc. The present study focuses on the rational development of (E)-3-(benzo[d][1,3]dioxol-5-yl)-1-(1-methoxy-9H-carbazol-3-yl)prop-2-en-1-one from murrayanine and 3′,4′-(methylenedioxy)acetophenone and investigating the anti-inflammatory activity of the fabricated …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 9, Issue 1, 2018 · pp. 12–16 Read article