Trends in Drug Delivery

Formulation And Evaluation of Anti-Microbial Cream by Using Cucurbita Pepo Seed Oil

  1. Blessy Jacob
  2. Divya C
  3. Manoj Kumar N
  4. Nikkon Shil
  5. Rakshith S
  6. Pallavi BN.

Abstract

This study is focused on the “Formulation and evaluation of anti-microbial cream from Cucurbita pepo seed oil. This combination contained fresh seed oil extract from Cucurbita pepo belonging to family Cucurbitaceae. Pure Cucurbita pepo essential oil was collected in store. This is extracted cold pressed method. This seed oil contains tocopherol, sterols, carotenoids, vitamin C, vitamin A, Zn, Mg, fatty acids (omega-6 and omega-3 fatty acids. Cucurbita pepo seed oil, beeswax, borax, distilled water and other excipients are used in the formulation of antimicrobial cream. Four formulations F1, F2, F3, and F4 was formulated using different concentration of beeswax and seed oil. To determine whether formulation are superior, the physical appearance, spreadability, irritancy, washability, stability, pH, viscosity, test for emulsion (dye test and dilution test), and antimicrobial activity of formulation will be evaluated in the laboratory. During the research period we found F3 formulation was good and there was no phase separation, and it was showing antimicrobial activity so choose F3 as the good formulation.Keywords: anti-microbial cream, formulations, Cucurbita pepo seed oil
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